Masteron (Drostanolone Propionate-100mgs/ml)
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Masteron, Drostanolone, Dromostanolone, Drostanolone Propionate, Drostanolone Enanthate
Pharma brand names: Drolban
Originally Dromostanolone (abbreviated to Drostanolone) known by trade name Masteron is an injectable oil-based anabolic steroid, derived from Dihydrotestosterone (DHT). It is a member of the DHT-derived family of anabolic steroids. Other known DHT-derivatives include: Winstrol, Anadrol, Anavar, Primobolan, and a few more. Drostanolone (Masteron) is considered a moderate strength anabolic steroid with anabolic rating: 62 – 130 and low androgenic strenght: 25 – 40.
There are two different variants of Masteron:
All anabolic steroid analogues and derivatives are derivates of the three natural anabolic steroids found in the human body:
Biochemistry of Masteron / Drostanolone
Masteron is a modified form of Dihydrotestosterone, with a methyl group at the 2nd carbon (carbon alpha) atom. This modification is responsible for the anabolic strength increase. This methyl group makes it harder for the enzyme 3-hydroxysteroid dehydrogenase to metabolize Masteron. This enzyme is abundantly present in muscle tissue, and is responsible for degrading any DHT into two inactive metabolites: 3-Alpha Androstanediol and 3-Beta Androstanediol. Because of this enzyme DHT is not anabolic in muscle tissue at all. It is believed that if the enzyme 3-hydroxysteroid dehydrogenase was neutralized, DHT would actually be a very powerful anabolic steroid. Drostanolone’s methyl group addition makes it imune to this enzyme.
Drostanolone is injected into the body as an ester (bonded to either Propionate or Enanthate). Enzymes cleave off the ester from the Masteron molecule – which takes varying amount of time depending on which ester was used. This process causes the gradual release rate and extended half-life of the steroid. Drostanolone Propionate has a half-life of 2.5 days, while Drostanolone Enanthate has a half-life of 10 days.
Intended use of Drostanolone
was initially marketed as a treatment of female breast cancer. Because it pronounced male characteristics in women and because more effective breast cancer treatments were invented, Drostanolone was gradually phased out.
Actual use of Masteron
Nowadays Drostanolone is a very popular anabolic steroid used mainly by athletes and bodybuilders.
How to use Masteron?
Where to inject Drostanolone / Masteron
Like other steroids Masteron can be injected into any muscle (if the muscle is big enough). The most popular being buttocks, shoulders and triceps.
Masteron cycle compatibility, examples and duration
Like majority of steroids, Masteron acts very well in combination with Human Growth Hormone (4IU per day).
Effects of Drostanolone / Masteron (desirable)
There are principally two desirable effects of Testosterone:
physical / athletic performance enhancement (endurance, strength, faster regeneration)
physique enhancement (muscle buildup, fat loss)
The rest of desirable testosterone effects that an individual might experience during the steroid cycle, include:
increase in collagen synthesis and bone mineral content. Collagen is the protein-based construction material for connective tissues throughout the body (the ligaments, tendons, cartilage, joints, and bones).
heightened self esteem
deeper (manly) voice
darkening and thickening of body hair
increase in levels of IGF-1 and MGF hormones (which also promote muscle growth)
increased hemoglobin (red blood cell count)
anti-catabolic effect on muscle tissues by way of acting as an anti-glucocorticoid
Side effects of Testosterone Propionate (and how to counter them)
Internet / forum rumors
It is rumored that Propionate is better for cutting and fat loss phases, and it supposedly causes less water retention than other esterified types of Testosterone. This is simply nonsense that has been passed on by people developing improper conclusions not based on scientific reasoning. Propionater (like any other ester bonded to Testosterone) is always broken off by enzymes in the body, after which 100% pure bio-identical Testosterone is left as a result. This Testosterone is then free to do its job in the body. The same occurs with any and all esterified forms of Testosterone. Therefore, the only possible difference that esterification causes to Testosterone effects is its half-life and rate of release. The esters only determine how much Testosterone is released into the bloodstream per given time frame.