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Ionamine 30MG, IONAMIN ’15’ and IONAMIN ’30’ contain 15 mg and 30 mg respectively of phentermine as the cationic exchange resin complex. Phentermine is a, a-dimethyl phenethylamine (phenyl-tertiary-butylamine).
Ionamine 30MG, IONAMIN Capsules are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index ≥ 30 kg/m², or ≥ 27 kg/m² in the presence of other risk factors (e.g., hypertension, diabetes, hyperlipidemia).
Below is a chart of Body Mass Index (BMI) based on various heights and weights.
BMI is calculated by taking the patient’s weight, in kilograms (kg), divided by the patient’s height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches x 0.0254 = meters.
One capsule daily, before breakfast or 10-14 hours before retiring. For individuals exhibiting greater drug responsiveness, IONAMIN ’15’ will usually suffice. IONAMIN ’30’ is recommended for less responsive patients. Ionamine 30MG is not recommended for use in pediatric patients under 16 years of age.
Ionamine 30MG Capsules should be swallowed whole.
Ionamine 30MG (phentermine resin) Capsules are available in two strengths:
15 mg, yellow/grey capsules, imprinted with “IONAMIN 15.”
NDC 53014-903-71 Bottle of 100’s
NDC 53014-903-84 Bottle of 400’s
30 mg, yellow/yellow capsules, imprinted with “IONAMIN 30.”
NDC 53014-904-71 Bottle of 100’s
NDC 53014-904-84 Bottle of 400’s
Dispense in a tight container. Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F) [See USP Controlled Room Temperature]. Keep out of the reach of children.
Cardiovascular: Primary pulmonary hypertension (see WARNINGS), palpitation, tachycardia, elevation of blood pressure.
Central Nervous System: Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache; rarely psychotic episodes at recommended doses with some drugs in this class.
Gastrointestinal: Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.
Endocrine: Impotence, changes in libido.
In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of phentermine. However in the presence of topiramate, phentermine Cmax and AUC increase 13% and 42% respectively.